Session 1: Clinical Examples of the Roles of Mechanical Forces in Tissues and Organs: The Working Paradigms (Instructors present/debate silicone breast implant controversy)
Part I: Unit Cell Processes and Unit Tissue Structure; Effects of Exogenous Forces
Session 2: Unit Cell Processes
Session 3: Tissue Structures and Cell-Matrix Interactions: Integrins
Session 4: Support Structures: Molecules and Tissues
Session 5: Thermodynamics of ECM Deformation
Session 6: Effects of Exogenous Mechanical Forces on Cells/Tissues
Session 7: Effects of Pressure Waves on Tissue: Extracorporeal Shock Wave I
Session 8: Student presentations: term report candidate topics; review
Session 9: Quiz 1
Part II: Mechanics of Cells and Matrix Molecules; Endogenous Force Generation
Session 10: Response of Chondrocytes to Mechanical Strain
Session 11: Endogenous Mechanical Force Generation by Cells
Session 12: Models for Cell Contraction In Vitro
Session 13: Coupling of Cells with Other Cells
Session 14: Coupling of Cells with Matrix
Session 15: Integrin-Ligand Interactions during Regeneration
Session 16: Linear Elastic Models of Tissues
Session 17: Quiz 2
Part III: Tissue Mechanics
Session 18: Student Presentations: Term Report Progress
Session 19: Mechanical Behavior of Bone and Response to Loading
Session 20: Musculoskeletal Soft Tissue Mechanics I
Session 21: Musculoskeletal Soft Tissue Mechanics II
Session 22: Poroelastic Models, Cartilage
Session 23: Viscoelastic Behavior of Tissues, Skin, Cartilage
Session 24: Oral presentation of term reports; written report due
Session 25: Review
Session 26: Quiz 3
