2.785J | Fall 2016 | Graduate

Cell-Matrix Mechanics

Lecture Notes and Readings

Chapter 1: Clinical Examples of the Roles of Mechanical Forces in Tissue and Organ Development and Maintenance: The Working Paradigm (external)

Part I: Unit Cell Processes and Unit Tissue Structure; Effects of Exogenous Forces

Chapter 2: Unit Tissue Structure and Unit Cell Processes (external)

Chapter 3: Cell-Matrix Interaction: Integrins and Fibronexus (external)

Chapter 4: Matrix Composition (external)

Part II: Mechanics of Cells and Matrix Molecules; Endogenous Force Generation

Chapter 5: Mechanical Behavior of Biological Matrix Components (external)

Chapter 6: Effects of Exogenous Mechanical Forces on Cells (external)

Chapter 7: Endogenous Mechanical Force Generation and Effects (external)

Part III: Tissue Mechanics

Chapter 8: Tendon and Ligament: Mechanical Constitutive Equations and Biomechanics (external)

Chapter 9: Meniscus and Intervertebral Disc (external)

Chapter 10: Articular Cartilage (external)

Chapter 11: Bone (external)

Chapter 12: Other: Biomaterials and Electrically and Magnetically Responsive Matrices (external)